British Air Force Typhoon jets have operated alongside French aircraft in a combined operation targeting an subterranean weapons facility in Syrian territory operated by the Daesh militant organization, as stated by the British defence ministry.
The location, located using intelligence, was thought to be containing munitions and bombs, the statement said, and was located in mountains just above the ancient city of Palmyra in Syria's central region.
"The RAF jets used Paveway IV guided bombs to target a several entry passages leading to the facility... preliminary assessments are that the target was engaged successfully," the MoD said.
There was no sign of any civilian casualties in the strike late on Saturday and all the aircraft made a safe return, the MoD added.
The British jets were supported by a Voyager refuelling tanker.
IS - referred to as Daesh - enforced militant control over significant areas in Syria and Iraq prior to its 2019 collapse.
"This action underscores the UK's leading role, and commitment to operate in unison with allied nations, to eliminate any revival of the terrorist group and their harmful and extremist ideologies in the Middle East," the British Defence Secretary the Defence Secretary remarked.
UK warplanes have carried out surveillance missions over Syria to "deter any attempted comeback" of Islamic State subsequent to its military defeat at the climactic battle in Baghuz in 2019, the authorities noted.
"I must thank every member of our armed forces involved in this mission for their professionalism and their courage," the Defence Secretary commented. "They were among numerous British personnel deployed over Christmas and New Year. This mission, to eliminate militants who endanger our safety, shows how UK forces are ready to step up, all year round, keeping Britain secure at home and influential overseas."
In December, the American forces conducted what it termed a "large-scale strike" against IS targets in the country, following an assault claimed the lives of two American soldiers and a civilian interpreter in Palmyra.
The United Nations says Islamic State still maintains roughly 5-7 thousand combatants in Iraq and Syria.